LaRochelle JR, Fodor M, Ellegast JM, et al. Identification of an allosteric benzothiazolopyrimidone inhibitor of the oncogenic protein tyrosine phosphatase SHP2. Bioorg Med Chem. 2017;25(24):6479-6485. doi:10.1016/j.bmc.2017.10.025
Andreotti AH, Bunnell SC, Feng S, Berg LJ, Schreiber SL. Regulatory intramolecular association in a tyrosine kinase of the Tec family. Nature. 1997;385(6611):93-7. doi:10.1038/385093a0
Schreiber SL, Crabtree GR. The mechanism of action of cyclosporin A and FK506. Immunol Today. 1992;13(4):136-42. doi:10.1016/0167-5699(92)90111-J
Comer E, Rohan E, Deng L, Porco JA. An approach to skeletal diversity using functional group pairing of multifunctional scaffolds. Org Lett. 2007;9(11):2123-6. doi:10.1021/ol070606t
Spaulding CN, Klein RD, Ruer S, et al. Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist. Nature. 2017;546(7659):528-532. doi:10.1038/nature22972
Gaudelli NM, Komor AC, Rees HA, et al. Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage. Nature. 2017;551(7681):464-471. doi:10.1038/nature24644
Crabtree GR, Schreiber SL. Three-part inventions: intracellular signaling and induced proximity. Trends Biochem Sci. 1996;21(11):418-22.
Schreiber SL, Liu J, Albers MW, et al. Immunophilin-ligand complexes as probes of intracellular signaling pathways. Transplant Proc. 1991;23(6):2839-44.
Farutin V, Robison K, Lightcap E, et al. Edge-count probabilities for the identification of local protein communities and their organization. Proteins. 2006;62(3):800-18. doi:10.1002/prot.20799
Zhu J, Zhou Q, Shang Y, et al. Synaptic Targeting and Function of SAPAPs Mediated by Phosphorylation-Dependent Binding to PSD-95 MAGUKs. Cell Rep. 2017;21(13):3781-3793. doi:10.1016/j.celrep.2017.11.107