Shen K, Huang RK, Brignole EJ, et al. Architecture of the human GATOR1 and GATOR1-Rag GTPases complexes. Nature. 2018;556(7699):64-69. doi:10.1038/nature26158
Feng S, Kapoor TM, Shirai F, Combs AP, Schreiber SL. Molecular basis for the binding of SH3 ligands with non-peptide elements identified by combinatorial synthesis. Chem Biol. 1996;3(8):661-70.
Hawley RC, Kiessling LL, Schreiber SL. Model of the interactions of calichemicin gamma 1 with a DNA fragment from pBR322. Proc Natl Acad Sci U S A. 1989;86(4):1105-9.
Agarwala R, Batzoglou S, Dančík V, et al. Local rules for protein folding on a triangular lattice and generalized hydrophobicity in the HP model. J Comput Biol. 1997;4(3):275-96. doi:10.1089/cmb.1997.4.275
Xiong T, Meister GE, Workman RE, et al. Targeted DNA methylation in human cells using engineered dCas9-methyltransferases. Sci Rep. 2017;7(1):6732. doi:10.1038/s41598-017-06757-0
Agostini M, Schoenmakers E, Beig J, et al. A Pharmacogenetic Approach to the Treatment of Patients With Mutations. Diabetes. 2018;67(6):1086-1092. doi:10.2337/db17-1236
Kuai L, Ong SE, Madison JM, et al. AAK1 identified as an inhibitor of neuregulin-1/ErbB4-dependent neurotrophic factor signaling using integrative chemical genomics and proteomics. Chem Biol. 2011;18(7):891-906. doi:10.1016/j.chembiol.2011.03.017
Zhou G, Ferrer M, Chopra R, et al. The structure of an HIV-1 specific cell entry inhibitor in complex with the HIV-1 gp41 trimeric core. Bioorg Med Chem. 2000;8(9):2219-27.
Chan P, Han X, Zheng B, et al. Autopalmitoylation of TEAD proteins regulates transcriptional output of the Hippo pathway. Nat Chem Biol. 2016;12(4):282-9. doi:10.1038/nchembio.2036
Yamano T, Zetsche B, Ishitani R, Zhang F, Nishimasu H, Nureki O. Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1. Mol Cell. 2017;67(4):633-645.e3. doi:10.1016/j.molcel.2017.06.035