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Adipocyte glucocorticoid receptor is important in lipolysis and insulin resistance due to exogenous steroids, but not insulin resistance caused by high fat feeding.

Shen Y, Roh HC, Kumari M, Rosen ED. Adipocyte glucocorticoid receptor is important in lipolysis and insulin resistance due to exogenous steroids, but not insulin resistance caused by high fat feeding. Mol Metab. 2017;6(10):1150-1160. doi:10.1016/j.molmet.2017.06.013

Genetic Evidence That Carbohydrate-Stimulated Insulin Secretion Leads to Obesity.

Astley CM, Todd JN, Salem RM, et al. Genetic Evidence That Carbohydrate-Stimulated Insulin Secretion Leads to Obesity. Clin Chem. 2018;64(1):192-200. doi:10.1373/clinchem.2017.280727

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity.

Joshi PK, Pirastu N, Kentistou KA, et al. Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity. Nat Commun. 2017;8(1):910. doi:10.1038/s41467-017-00934-5

Defective STIM-mediated store operated Ca entry in hepatocytes leads to metabolic dysfunction in obesity.

Arruda AP, Pers BM, Parlakgul G, et al. Defective STIM-mediated store operated Ca entry in hepatocytes leads to metabolic dysfunction in obesity. Elife. 2017;6. doi:10.7554/eLife.29968

Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions.

Shungin D, Deng WQ, Varga TV, et al. Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions. PLoS Genet. 2017;13(6):e1006812. doi:10.1371/journal.pgen.1006812

Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity.

Bartelt A, Widenmaier SB, Schlein C, et al. Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity. Nat Med. 2018;24(3):292-303. doi:10.1038/nm.4481

ER Stress Promotes Inflammation through Re-wIREd Macrophages in Obesity.

Garfinkel BP, Hotamışlıgil GS. ER Stress Promotes Inflammation through Re-wIREd Macrophages in Obesity. Mol Cell. 2017;66(6):731-733. doi:10.1016/j.molcel.2017.05.037

Diet, Genetics, and the Gut Microbiome Drive Dynamic Changes in Plasma Metabolites.

Fujisaka S, Avila-Pacheco J, Soto M, et al. Diet, Genetics, and the Gut Microbiome Drive Dynamic Changes in Plasma Metabolites. Cell Rep. 2018;22(11):3072-3086. doi:10.1016/j.celrep.2018.02.060

Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index.

Hoggart CJ, Venturini G, Mangino M, et al. Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index. PLoS Genet. 2014;10(7):e1004508. doi:10.1371/journal.pgen.1004508

Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity.

Fu S, Yalcin A, Lee GY, et al. Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity. Sci Transl Med. 2015;7(292):292ra98. doi:10.1126/scitranslmed.aaa9134