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Metabolomics Platform
Li Z, Li X, Zhou H, et al. A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies. Nature methods. 2022;19(12):1599-1611. doi:10.1038/s41592-022-01640-x
Shindyapina A V, Cho Y, Kaya A, et al. Rapamycin treatment during development extends life span and health span of male mice and . Science advances. 2022;8(37):eabo5482. doi:10.1126/sciadv.abo5482
Kelly RS, Mendez KM, Huang M, et al. Metabo-Endotypes of Asthma Reveal Differences in Lung Function: Discovery and Validation in Two TOPMed Cohorts. American journal of respiratory and critical care medicine. 2022;205(3):288-299. doi:10.1164/rccm.202105-1268OC
Chen TK, Coca SG, Estrella MM, et al. Longitudinal TNFR1 and TNFR2 and Kidney Outcomes: Results from AASK and VA NEPHRON-D. Journal of the American Society of Nephrology : JASN. 2022;33(5):996-1010. doi:10.1681/ASN.2021060735
Yao L, D’Agostino GD, Park J, et al. A biosynthetic pathway for the selective sulfonation of steroidal metabolites by human gut bacteria. Nature microbiology. 2022;7(9):1404-1418. doi:10.1038/s41564-022-01176-y
Heianza Y, Wang X, Rood J, et al. Changes in circulating bile acid subtypes in response to weight-loss diets are associated with improvements in glycemic status and insulin resistance: The POUNDS Lost trial. Metabolism: clinical and experimental. 2022;136:155312. doi:10.1016/j.metabol.2022.155312
Kang JH, Zeleznik O, Frueh L, et al. Prediagnostic Plasma Metabolomics and the Risk of Exfoliation Glaucoma. Investigative ophthalmology & visual science. 2022;63(9):15. doi:10.1167/iovs.63.9.15
Murthy VL, Nayor M, Carnethon M, et al. Circulating metabolite profile in young adulthood identifies long-term diabetes susceptibility: the Coronary Artery Risk Development in Young Adults (CARDIA) study. Diabetologia. 2022;65(4):657-674. doi:10.1007/s00125-021-05641-x
Selvaraj MS, Li X, Li Z, et al. Whole genome sequence analysis of blood lipid levels in >66,000 individuals. Nature communications. 2022;13(1):5995. doi:10.1038/s41467-022-33510-7