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Cancer Program
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Wu Z, Zhou J, Zhang X, et al. Reprogramming of the esophageal squamous carcinoma epigenome by SOX2 promotes ADAR1 dependence. Nat Genet. 2021;53(6):881-894. doi:10.1038/s41588-021-00859-2
Henley MJ, Koehler AN. Advances in targeting ’undruggable’ transcription factors with small molecules. Nat Rev Drug Discov. 2021. doi:10.1038/s41573-021-00199-0
Shareef SJ, Bevill SM, Raman AT, et al. Extended-representation bisulfite sequencing of gene regulatory elements in multiplexed samples and single cells. Nat Biotechnol. 2021. doi:10.1038/s41587-021-00910-x
Griffin GK, Wu J, Iracheta-Vellve A, et al. Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity. Nature. 2021. doi:10.1038/s41586-021-03520-4