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Publications

CLEC16A in astrocytes promotes mitophagy and limits pathology in a multiple sclerosis mouse model.

Kadowaki A, Wheeler MA, Li Z, et al. CLEC16A in astrocytes promotes mitophagy and limits pathology in a multiple sclerosis mouse model. Nature neuroscience. 2025. doi:10.1038/s41593-025-01875-9

Impact of DNA repair deficiency on sensitivity to antibody-drug conjugate (ADC) payloads in bladder cancer.

Shanmugam SP, Zhou Y, Stelter I, et al. Impact of DNA repair deficiency on sensitivity to antibody-drug conjugate (ADC) payloads in bladder cancer. Bladder cancer (Amsterdam, Netherlands). 2025;11(1):23523735251317865. doi:10.1177/23523735251317865

Improving the therapeutic profile of MSCs: Cytokine priming reduces donor-dependent heterogeneity and enhances their immunomodulatory capacity.

Valencia J, Yáñez RM, Muntión S, et al. Improving the therapeutic profile of MSCs: Cytokine priming reduces donor-dependent heterogeneity and enhances their immunomodulatory capacity. Frontiers in immunology. 2025;16:1473788. doi:10.3389/fimmu.2025.1473788

Use of patient-derived organotypic tumor spheroids for testing of viral vector gene therapy in combination with checkpoint blockade.

Domingues ACM, de Oliveira SB, Tessarollo NG, et al. Use of patient-derived organotypic tumor spheroids for testing of viral vector gene therapy in combination with checkpoint blockade. Molecular therapy. Oncology. 2025;33(1):200942. doi:10.1016/j.omton.2025.200942

Distinct rates of VUS reclassification are observed when subclassifying VUS by evidence level.

Bennett G, Karbassi I, Chen W, et al. Distinct rates of VUS reclassification are observed when subclassifying VUS by evidence level. Genetics in medicine : official journal of the American College of Medical Genetics. 2025:101400. doi:10.1016/j.gim.2025.101400

Impact of Social Determinants of Health on Cardiovascular Disease.

Bazoukis G, Loscalzo J, Hall JL, Bollepalli SC, Singh JP, Armoundas AA. Impact of Social Determinants of Health on Cardiovascular Disease. Journal of the American Heart Association. 2025;14(5):e039031. doi:10.1161/JAHA.124.039031

Predicting future risk of developing cognitive impairment using ambulatory sleep EEG: Integrating univariate analysis and multivariate information theory approach.

Haghayegh S, Herzog R, Bennett DA, et al. Predicting future risk of developing cognitive impairment using ambulatory sleep EEG: Integrating univariate analysis and multivariate information theory approach. Journal of Alzheimer’s disease : JAD. 2025:13872877251319742. doi:10.1177/13872877251319742

Predicting Milk Flow Behavior in Human Lactating Breast: An Integrated Machine Learning and Computational Fluid Dynamics Approach.

Olapojoye AO, Zaheri S, Nosratinia A, Hassanipour F. Predicting Milk Flow Behavior in Human Lactating Breast: An Integrated Machine Learning and Computational Fluid Dynamics Approach. Journal of biomechanical engineering. 2025:1-16. doi:10.1115/1.4068077

Structurally Oriented Classification of FOXA1 Alterations Identifies Prostate Cancers with Opposing Clinical Outcomes and Distinct Molecular and Immunologic Subtypes.

Hwang J, Likasitwatanakul P, Deshmukh SK, et al. Structurally Oriented Classification of FOXA1 Alterations Identifies Prostate Cancers with Opposing Clinical Outcomes and Distinct Molecular and Immunologic Subtypes. Clinical cancer research : an official journal of the American Association for Cancer Research. 2025;31(5):936-948. doi:10.1158/1078-0432.CCR-24-3471

Prevalence and disease risks for male and female sex chromosome trisomies: a registry-based phenome-wide association study in 1.5 million participants of MVP, FinnGen, and UK Biobank.

Davis SM, Liu A, Teerlink CC, et al. Prevalence and disease risks for male and female sex chromosome trisomies: a registry-based phenome-wide association study in 1.5 million participants of MVP, FinnGen, and UK Biobank. medRxiv : the preprint server for health sciences. 2025. doi:10.1101/2025.01.31.25321488