Publications

Molecular hallmarks of excitatory and inhibitory neuronal resilience and resistance to Alzheimer's disease.

Castanho I, Yeganeh PN, Boix CA, et al. Molecular hallmarks of excitatory and inhibitory neuronal resilience and resistance to Alzheimer’s disease. bioRxiv : the preprint server for biology. 2025. doi:10.1101/2025.01.13.632801

Combined PARP14 inhibition and PD-1 blockade promotes cytotoxic T cell quiescence and modulates macrophage polarization in relapsed melanoma.

Leshem R, Sefton KN, Wong CW, et al. Combined PARP14 inhibition and PD-1 blockade promotes cytotoxic T cell quiescence and modulates macrophage polarization in relapsed melanoma. Journal for immunotherapy of cancer. 2025;13(1). doi:10.1136/jitc-2024-010683

Integrating representation learning, permutation, and optimization to detect lineage-related gene expression patterns.

Schlüter HM, Uhler C. Integrating representation learning, permutation, and optimization to detect lineage-related gene expression patterns. Nature communications. 2025;16(1):1062. doi:10.1038/s41467-025-56388-7

A compendium of Amplification-Related Gain Of Sensitivity genes in human cancer.

Rendo V, Schubert M, Khuu N, et al. A compendium of Amplification-Related Gain Of Sensitivity genes in human cancer. Nature communications. 2025;16(1):1077. doi:10.1038/s41467-025-56301-2

A genome-wide atlas of human cell morphology.

Ramezani M, Weisbart E, Bauman J, et al. A genome-wide atlas of human cell morphology. Nature methods. 2025. doi:10.1038/s41592-024-02537-7

Activated Cardiac Fibroblasts are a Primary Source High Molecular Weight Hyaluronan Production.

Little DT, Howard CM, Pendergraft E, et al. Activated Cardiac Fibroblasts are a Primary Source High Molecular Weight Hyaluronan Production. American journal of physiology. Cell physiology. 2025. doi:10.1152/ajpcell.00786.2024

The meninges host a distinct compartment of regulatory T cells that preserves brain homeostasis.

Marin-Rodero M, Cintado E, Walker AJ, et al. The meninges host a distinct compartment of regulatory T cells that preserves brain homeostasis. Science immunology. 2025:eadu2910. doi:10.1126/sciimmunol.adu2910

Early transcriptional effects of inflammatory cytokines reveal highly redundant cytokine networks.

Lee JJ, Yang L, Kotzin JJ, et al. Early transcriptional effects of inflammatory cytokines reveal highly redundant cytokine networks. The Journal of experimental medicine. 2025;222(4). doi:10.1084/jem.20241207

Machine learning for synthetic gene circuit engineering.

Palacios S, Collins JJ, Del Vecchio D. Machine learning for synthetic gene circuit engineering. Current opinion in biotechnology. 2025;92:103263. doi:10.1016/j.copbio.2025.103263

Correction: Assessment and ascertainment in psychiatric molecular genetics: challenges and opportunities for cross-disorder research.

Cai N, Verhulst B, Andreassen OA, et al. Correction: Assessment and ascertainment in psychiatric molecular genetics: challenges and opportunities for cross-disorder research. Molecular psychiatry. 2025. doi:10.1038/s41380-025-02914-4

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Publications

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