ӳ��ý

Publications

Mutant RIT1 cooperates with YAP to drive an EMT-like lung cancer state.

Rominger MC, Gupta S, Moorthi S, et al. Mutant RIT1 cooperates with YAP to drive an EMT-like lung cancer state. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.11.11.623044

PrP turnover in vivo and the time to effect of prion disease therapeutics.

Corridon TL, O’Moore J, Lian Y, et al. PrP turnover in vivo and the time to effect of prion disease therapeutics. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.11.12.623215

Mapping rare protein-coding variants on multi-organ imaging traits.

Fan Y, Chen J, Fan Z, et al. Mapping rare protein-coding variants on multi-organ imaging traits. medRxiv : the preprint server for health sciences. 2024. doi:10.1101/2024.11.16.24317443

Distinct rates of VUS reclassification are observed when subclassifying VUS by evidence level.

Bennett G, Karbassi I, Chen W, et al. Distinct rates of VUS reclassification are observed when subclassifying VUS by evidence level. medRxiv : the preprint server for health sciences. 2024. doi:10.1101/2024.11.13.24317242

Molecular convergence of risk variants for congenital heart defects leveraging a regulatory map of the human fetal heart.

Ma R, Conley SD, Kosicki M, et al. Molecular convergence of risk variants for congenital heart defects leveraging a regulatory map of the human fetal heart. medRxiv : the preprint server for health sciences. 2024. doi:10.1101/2024.11.20.24317557

The ClinGen Syndromic Disorders Gene Curation Expert Panel: Assessing the Clinical Validity of 111 Gene-Disease Relationships.

Broeren E, Gitau V, Byrne A, et al. The ClinGen Syndromic Disorders Gene Curation Expert Panel: Assessing the Clinical Validity of 111 Gene-Disease Relationships. medRxiv : the preprint server for health sciences. 2024. doi:10.1101/2024.11.19.24317561

Single cell variant to enhancer to gene map for coronary artery disease.

Amrute JM, Lee PC, Eres I, et al. Single cell variant to enhancer to gene map for coronary artery disease. medRxiv : the preprint server for health sciences. 2024. doi:10.1101/2024.11.13.24317257

HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma.

Turnham RE, Pitea A, Jang GM, et al. HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma. Cancer research. 2024. doi:10.1158/0008-5472.CAN-24-0456

A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo.

Xie SC, Tai CW, Morton CJ, et al. A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo. PLoS pathogens. 2024;20(12):e1012429. doi:10.1371/journal.ppat.1012429

Robust self-supervised denoising of voltage imaging data using CellMincer.

Wang B, Ma T, Chen T, et al. Robust self-supervised denoising of voltage imaging data using CellMincer. Npj imaging. 2024;2(1):51. doi:10.1038/s44303-024-00055-x