Publications

Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery.

Bonev B, Gonçalo CB, Chen F, et al. Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery. Nature neuroscience. 2024;27(12):2292-2309. doi:10.1038/s41593-024-01806-0

Applying single-cell and single-nucleus genomics to studies of cellular heterogeneity and cell fate transitions in the nervous system.

Adameyko I, Bakken T, Bhaduri A, et al. Applying single-cell and single-nucleus genomics to studies of cellular heterogeneity and cell fate transitions in the nervous system. Nature neuroscience. 2024;27(12):2278-2291. doi:10.1038/s41593-024-01827-9

Implementation and validation of single-cell genomics experiments in neuroscience.

Colonna M, Konopka G, Liddelow SA, et al. Implementation and validation of single-cell genomics experiments in neuroscience. Nature neuroscience. 2024;27(12):2310-2325. doi:10.1038/s41593-024-01814-0

Global adherence to a healthy and sustainable diet and potential reduction in premature death.

Gu X, Bui LP, Wang F, Wang DD, Springmann M, Willett WC. Global adherence to a healthy and sustainable diet and potential reduction in premature death. Proceedings of the National Academy of Sciences of the United States of America. 2024;121(50):e2319008121. doi:10.1073/pnas.2319008121

Hospital-wide access to genomic data advanced pediatric rare disease research and clinical outcomes.

French CE, Andrews NC, Beggs AH, et al. Hospital-wide access to genomic data advanced pediatric rare disease research and clinical outcomes. NPJ genomic medicine. 2024;9(1):60. doi:10.1038/s41525-024-00441-9

Global adherence to a healthy and sustainable diet and potential reduction in premature death.

Gu X, Bui LP, Wang F, Wang DD, Springmann M, Willett WC. Global adherence to a healthy and sustainable diet and potential reduction in premature death. Proceedings of the National Academy of Sciences of the United States of America. 2024;121(50):e2319008121. doi:10.1073/pnas.2319008121

A cautionary tale for Alzheimer's disease GWAS by proxy.

Pedersen EM, Wimberley T, Vilhjálmsson BJ. A cautionary tale for Alzheimer’s disease GWAS by proxy. Nature genetics. 2024. doi:10.1038/s41588-024-02023-y

Therapeutic hypoxia for mitochondrial disease via enhancement of hemoglobin affinity and inhibition of HIF-2α.

Wang H, Miranda M, Marutani E, et al. Therapeutic hypoxia for mitochondrial disease via enhancement of hemoglobin affinity and inhibition of HIF-2α. The Journal of clinical investigation. 2024;134(23). doi:10.1172/JCI185569

Epigenetic and Oncogenic Inhibitors Cooperatively Drive Differentiation and Kill KRAS-Mutant Colorectal Cancers.

Loi P, Schade AE, Rodriguez CL, et al. Epigenetic and Oncogenic Inhibitors Cooperatively Drive Differentiation and Kill KRAS-Mutant Colorectal Cancers. Cancer discovery. 2024;14(12):2430-2449. doi:10.1158/2159-8290.CD-23-0866

Aladyn Individual: Bayesian Hierarchical Dynamic Genetic Modeling of Comorbidity Progression.

Urbut S, Ding Y, Jiang X, et al. Aladyn Individual: Bayesian Hierarchical Dynamic Genetic Modeling of Comorbidity Progression. medRxiv : the preprint server for health sciences. 2024. doi:10.1101/2024.09.29.24314557