Loi P, Schade AE, Rodriguez CL, et al. Epigenetic and Oncogenic Inhibitors Cooperatively Drive Differentiation and Kill KRAS-Mutant Colorectal Cancers. Cancer discovery. 2024;14(12):2430-2449. doi:10.1158/2159-8290.CD-23-0866
Publications
Urbut S, Ding Y, Jiang X, et al. Aladyn Individual: Bayesian Hierarchical Dynamic Genetic Modeling of Comorbidity Progression. medRxiv : the preprint server for health sciences. 2024. doi:10.1101/2024.09.29.24314557
Merk DJ, Tsiami F, Hirsch S, et al. Functional screening reveals genetic dependencies and diverging cell cycle control in atypical teratoid rhabdoid tumors. Genome biology. 2024;25(1):301. doi:10.1186/s13059-024-03438-w
Ziegler AK, Scheele C. Human adipose depots’ diverse functions and dysregulations during cardiometabolic disease. npj metabolic health and disease. 2024;2(1):34. doi:10.1038/s44324-024-00036-z
Boßelmann CM, Leu C, Brünger T, et al. Analysis of 1386 epileptogenic brain lesions reveals association with DYRK1A and EGFR. Nature communications. 2024;15(1):10429. doi:10.1038/s41467-024-54911-w
Luo Y, Huang CC, Howard NC, et al. Paired analysis of host and pathogen genomes identifies determinants of human tuberculosis. Nature communications. 2024;15(1):10393. doi:10.1038/s41467-024-54741-w
Gelabert P, Bickle P, Hofmann D, et al. Social and genetic diversity in first farmers of central Europe. Nature human behaviour. 2024. doi:10.1038/s41562-024-02034-z
Mathews EW, Coffey SR, Gärtner A, et al. Suppression of Huntington’s Disease Somatic Instability by Transcriptional Repression and Direct CAG Repeat Binding. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.11.04.619693
Yammine KM, Abularach SM, Xiong M, et al. Human cartilage model of the precocious osteoarthritis-inducing p.Arg719Cys reveals pathology-driving matrix defects and a failure of the ER proteostasis network to recognize the defective procollagen-II. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.11.07.622468
MacDonald L, Elmesmari A, Somma D, et al. Synovial tissue myeloid dendritic cell subsets exhibit distinct tissue-niche localization and function in health and rheumatoid arthritis. Immunity. 2024. doi:10.1016/j.immuni.2024.11.004