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Koblan LW, Arbab M, Shen MW, et al. Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning. Nature biotechnology. 2021;39(11):1414-1425. doi:10.1038/s41587-021-00938-z

Hanna RE, Hegde M, Fagre C, et al. Massively parallel assessment of human variants with base editor screens. Cell. 2021;184(4):1064-1080.e20. doi:10.1016/j.cell.2021.01.012

Suh S, Choi EH, Leinonen H, et al. Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing. Nature biomedical engineering. 2021;5(2):169-178. doi:10.1038/s41551-020-00632-6

Modell AE, Lai S, Nguyen TM, Choudhary A. Bifunctional modalities for repurposing protein function. Cell chemical biology. 2021;28(7):1081-1089. doi:10.1016/j.chembiol.2021.06.005

Krishnamurthy S, Traore S, Cooney AL, et al. Functional correction of CFTR mutations in human airway epithelial cells using adenine base editors. Nucleic acids research. 2021;49(18):10558-10572. doi:10.1093/nar/gkab788

Blum T, Liu H, Packer MS, et al. Phage-assisted evolution of botulinum neurotoxin proteases with reprogrammed specificity. Science (New York, N.Y.). 2021;371(6531):803-810. doi:10.1126/science.abf5972

Huang TP, Newby GA, Liu DR. Precision genome editing using cytosine and adenine base editors in mammalian cells. Nature protocols. 2021;16(2):1089-1128. doi:10.1038/s41596-020-00450-9

Newby GA, Liu DR. In vivo somatic cell base editing and prime editing. Molecular therapy : the journal of the American Society of Gene Therapy. 2021;29(11):3107-3124. doi:10.1016/j.ymthe.2021.09.002

Gao P, Lyu Q, Ghanam A, et al. Prime editing in mice reveals the essentiality of a single base in driving tissue-specific gene expression. Genome biology. 2021;22(1):83. doi:10.1186/s13059-021-02304-3