Lim D, Sreekanth V, Cox KJ, et al. Engineering designer beta cells with a CRISPR-Cas9 conjugation platform. Nature communications. 2020;11(1):4043. doi:10.1038/s41467-020-17725-0
Chemical Biology and Therapeutics Science Program
Sreekanth V, Zhou Q, Kokkonda P, et al. Chemogenetic System Demonstrates That Cas9 Longevity Impacts Genome Editing Outcomes. ACS central science. 2020;6(12):2228-2237. doi:10.1021/acscentsci.0c00129
Maji B, Gangopadhyay SA, Lee M, et al. A High-Throughput Platform to Identify Small-Molecule Inhibitors of CRISPR-Cas9. Cell. 2019;177(4):1067-1079.e19. doi:10.1016/j.cell.2019.04.009
Vinyard ME, Su C, Siegenfeld AP, et al. CRISPR-suppressor scanning reveals a nonenzymatic role of LSD1 in AML. Nat Chem Biol. 2019;15(5):529-539. doi:10.1038/s41589-019-0263-0
Manna D, Maji B, Gangopadhyay SA, et al. A Singular System with Precise Dosing and Spatiotemporal Control of CRISPR-Cas9. Angewandte Chemie (International ed. in English). 2019;58(19):6285-6289. doi:10.1002/anie.201900788
Cox KJ, Subramanian HKK, Samaniego C, Franco E, Choudhary A. A universal method for sensitive and cell-free detection of CRISPR-associated nucleases. Chemical science. 2019;10(9):2653-2662. doi:10.1039/c8sc03426e
Usanov DL, Chan AI, Maianti JP, Liu DR. Second-generation DNA-templated macrocycle libraries for the discovery of bioactive small molecules. Nat Chem. 2018;10(7):704-714. doi:10.1038/s41557-018-0033-8
Weidmann AG, Choudhary A. Special Issue on the Chemical Biology of CRISPR. ACS Chem Biol. 2018;13(2):283-284. doi:10.1021/acschembio.8b00134
Eaton JK, Furst L, Ruberto RA, et al. Targeting a Therapy-Resistant Cancer Cell State Using Masked Electrophiles as GPX4 Inhibitors. bioRxiv. 2018. doi:10.1101/376764
Andrew AL, Perry BW, Card DC, et al. Growth and stress response mechanisms underlying post-feeding regenerative organ growth in the Burmese python. BMC Genomics. 2017;18(1):338. doi:10.1186/s12864-017-3743-1