Vinyard ME, Su C, Siegenfeld AP, et al. CRISPR-suppressor scanning reveals a nonenzymatic role of LSD1 in AML. Nat Chem Biol. 2019;15(5):529-539. doi:10.1038/s41589-019-0263-0
Chemical Biology and Therapeutics Science Program
Manna D, Maji B, Gangopadhyay SA, et al. A Singular System with Precise Dosing and Spatiotemporal Control of CRISPR-Cas9. Angewandte Chemie (International ed. in English). 2019;58(19):6285-6289. doi:10.1002/anie.201900788
Cox KJ, Subramanian HKK, Samaniego C, Franco E, Choudhary A. A universal method for sensitive and cell-free detection of CRISPR-associated nucleases. Chemical science. 2019;10(9):2653-2662. doi:10.1039/c8sc03426e
Usanov DL, Chan AI, Maianti JP, Liu DR. Second-generation DNA-templated macrocycle libraries for the discovery of bioactive small molecules. Nat Chem. 2018;10(7):704-714. doi:10.1038/s41557-018-0033-8
Weidmann AG, Choudhary A. Special Issue on the Chemical Biology of CRISPR. ACS Chem Biol. 2018;13(2):283-284. doi:10.1021/acschembio.8b00134
Eaton JK, Furst L, Ruberto RA, et al. Targeting a Therapy-Resistant Cancer Cell State Using Masked Electrophiles as GPX4 Inhibitors. bioRxiv. 2018. doi:10.1101/376764
Andrew AL, Perry BW, Card DC, et al. Growth and stress response mechanisms underlying post-feeding regenerative organ growth in the Burmese python. BMC Genomics. 2017;18(1):338. doi:10.1186/s12864-017-3743-1
Maji B, Moore CL, Zetsche B, et al. Multidimensional chemical control of CRISPR-Cas9. Nat Chem Biol. 2017;13(1):9-11. doi:10.1038/nchembio.2224
Chaikind B, Bessen JL, Thompson DB, Hu JH, Liu DR. A programmable Cas9-serine recombinase fusion protein that operates on DNA sequences in mammalian cells. Nucleic Acids Res. 2016;44(20):9758-9770. doi:10.1093/nar/gkw707
Kato N, Comer E, Sakata-Kato T, et al. Diversity-oriented synthesis yields novel multistage antimalarial inhibitors. Nature. 2016;538(7625):344-349. doi:10.1038/nature19804